abstract：OBJECTIVE:We aimed at developing and cross-validating a mathematical prediction model for an optimal basal insulin infusion pattern for children with type 1 diabetes on continuous subcutaneous insulin infusion therapy (CSII). RESEARCH DESIGN AND METHODS:We used the German/Austrian DPV-Wiss database for quality control...

journal_title：Diabetes care

authors： Holterhus PM,Bokelmann J,Riepe F,Heidtmann B,Wagner V,Rami-Merhar B,Kapellen T,Raile K,Quester W,Holl RW,German\/Austrian DPV-Initiative and the German Pediatric CSII Working Group.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Diabetes is associated with oxidative stress and increased mortality, but a possible correlation between leukocyte-endothelium interactions, oxidative stress, and silent myocardial ischemia (SMI) is yet to be confirmed. RESEARCH DESIGN AND METHODS:Mitochondrial dysfunction and interactions between leukocytes...

journal_title：Diabetes care

authors： Hernandez-Mijares A,Rocha M,Rovira-Llopis S,Bañuls C,Bellod L,de Pablo C,Alvarez A,Roldan-Torres I,Sola-Izquierdo E,Victor VM

更新日期：2013-06-01 00:00:00

abstract：:In June 2012, 13 thought leaders convened in a Diabetes Care Editors' Expert Forum to discuss the concept of personalized medicine in the wake of a recently published American Diabetes Association/European Association for the Study of Diabetes position statement calling for a patient-centered approach to hyperglycemia...

journal_title：Diabetes care

authors： Raz I,Riddle MC,Rosenstock J,Buse JB,Inzucchi SE,Home PD,Del Prato S,Ferrannini E,Chan JC,Leiter LA,Leroith D,Defronzo R,Cefalu WT

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To improve prognosis, it is important to predict the incidence of renal failure and cardiovascular disease in type 2 diabetic patients before the progression to advanced nephropathy. We investigated the predictive effects of urinary liver-type fatty acid-binding protein (L-FABP), which is associated with rena...

journal_title：Diabetes care

authors： Araki S,Haneda M,Koya D,Sugaya T,Isshiki K,Kume S,Kashiwagi A,Uzu T,Maegawa H

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine whether impaired fasting plasma glucose (FPG) and type 2 diabetes may be risk factors for sudden cardiac death (SCD). RESEARCH DESIGN AND METHODS:This prospective study was based on 2,641 middle-aged men 42-60 years of age at baseline. Impaired FPG level (≥5.6 mmol/L) am...

journal_title：Diabetes care

authors： Laukkanen JA,Mäkikallio TH,Ronkainen K,Karppi J,Kurl S

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Women exhibit exaggerated renal hemodynamic responses to hyperglycemia, which may promote kidney disease progression. Our aim was to determine if increased nitric oxide generation by l-arginine infusion would reverse this deleterious response to clamped hyperglycemia in women with type 1 diabetes mellitus. R...

journal_title：Diabetes care

authors： Cherney DZ,Scholey JW,Sochett EB

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Evidence that midregional fragment of pro-A-type natriuretic peptide (MR-proANP) is a marker of mortality in patients with type 2 diabetes is limited. Therefore, we aimed to investigate the capabilities of MR-proANP in predicting mortality. We also investigated whether MR-proANP influences the relationship be...

journal_title：Diabetes care

authors： van Hateren KJ,Landman GW,Kleefstra N,Groenier KH,Struck J,Navis GJ,Bakker SJ,Houweling ST,van der Meer K,Bilo HJ

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, stimulates glycosuria and lowers glycemia in patients with type 2 diabetes (T2DM). The objective of this study was to assess the pharmacodynamics of ipragliflozin in T2DM patients with impaired renal function. RESEARCH DESIGN AND METHODS:Glycosuria w...

journal_title：Diabetes care

authors： Ferrannini E,Veltkamp SA,Smulders RA,Kadokura T

更新日期：2013-05-01 00:00:00

abstract：:Because the negative consequences of new-onset diabetes mellitus after transplantation (NODAT) diminish the significant gains of kidney transplantation, it is imperative to develop clinical interventions to reduce the incidence of NODAT. In this review, we discuss whether intensive lifestyle interventions that delay o...

journal_title：Diabetes care

authors： Chakkera HA,Weil EJ,Pham PT,Pomeroy J,Knowler WC

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The performance of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) was compared in screening for diabetes by an oral glucose tolerance test (OGTT) in patients undergoing coronary angiography (CAG). RESEARCH DESIGN AND METHODS:Patients without known diabetes admitted for CAG were eligible. OGTT a...

journal_title：Diabetes care

authors： Wang JS,Lee IT,Lee WJ,Lin SY,Fu CP,Ting CT,Lee WL,Liang KW,Sheu WH

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:An artificial pancreas (AP) that automatically regulates blood glucose would greatly improve the lives of individuals with diabetes. Such a device would prevent hypo- and hyperglycemia along with associated long- and short-term complications as well as ease some of the day-to-day burden of frequent blood gluc...

journal_title：Diabetes care

authors： Dassau E,Zisser H,Harvey RA,Percival MW,Grosman B,Bevier W,Atlas E,Miller S,Nimri R,Jovanovic L,Doyle FJ 3rd

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Transient neonatal diabetes mellitus 1 (TNDM1) is the most common cause of diabetes presenting at birth. Approximately 5% of the cases are due to recessive ZFP57 mutations, causing hypomethylation at the TNDM locus and other imprinted loci (HIL). This has consequences for patient care because it has impact on...

journal_title：Diabetes care

authors： Boonen SE,Mackay DJ,Hahnemann JM,Docherty L,Grønskov K,Lehmann A,Larsen LG,Haemers AP,Kockaerts Y,Dooms L,Vu DC,Ngoc CT,Nguyen PB,Kordonouri O,Sundberg F,Dayanikli P,Puthi V,Acerini C,Massoud AF,Tümer Z,Temple IK

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Determine the impact of islet transplantation on carotid intima-media thickness (CIMT), a marker for atherosclerosis, in type 1 diabetes without kidney disease. RESEARCH DESIGN AND METHODS:Consecutive case series of 15 adults (mean age [SD], 49 years [10 years]; 87% female) with type 1 diabetes for ≥5 years ...

journal_title：Diabetes care

authors： Danielson KK,Hatipoglu B,Kinzer K,Kaplan B,Martellotto J,Qi M,Mele A,Benedetti E,Oberholzer J

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Obesity is associated with alterations in corticolimbic-striatal brain regions involved in food motivation and reward. Stress and the presence of food cues may each motivate eating and engage corticolimibic-striatal neurocircuitry. It is unknown how these factors interact to influence brain responses and whet...

journal_title：Diabetes care

authors： Jastreboff AM,Sinha R,Lacadie C,Small DM,Sherwin RS,Potenza MN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN. RESEARCH DESIGN AND METHODS:In 1,165 American type 1 diabetic patients with and without DN selected...

journal_title：Diabetes care

authors： Gu HF,Zheng X,Abu Seman N,Gu T,Botusan IR,Sunkari VG,Lokman EF,Brismar K,Catrina SB

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To compare three continuous glucose monitoring (CGM) devices in subjects with type 1 diabetes under closed-loop blood glucose (BG) control. RESEARCH DESIGN AND METHODS:Six subjects with type 1 diabetes (age 52 ± 14 years, diabetes duration 32 ± 14 years) each participated in two 51-h closed-loop BG control e...

journal_title：Diabetes care

authors： Damiano ER,El-Khatib FH,Zheng H,Nathan DM,Russell SJ

更新日期：2013-02-01 00:00:00

abstract：:Given the importance of glycemic control in the development of diabetes complications, the plethora of tools now available to monitor the day-to-day trends in glycemia is remarkable. In this regard, self-monitoring of blood glucose (SMBG) has been considered a key component of patient management. Arguably, there remai...

journal_title：Diabetes care

authors： Polonsky WH,Fisher L

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To study how type 2 diabetes adversely affects brain volumes, changes in volume, and cognitive function. RESEARCH DESIGN AND METHODS:Regional brain volumes and ischemic lesion volumes in 1,366 women, aged 72-89 years, were measured with structural brain magnetic resonance imaging (MRI). Repeat scans were col...

journal_title：Diabetes care

authors： Espeland MA,Bryan RN,Goveas JS,Robinson JG,Siddiqui MS,Liu S,Hogan PE,Casanova R,Coker LH,Yaffe K,Masaki K,Rossom R,Resnick SM,WHIMS-MRI Study Group.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Observational studies have associated metformin use with a decreased risk of lung cancer incidence in patients with type 2 diabetes, but the studies had important methodological shortcomings. The objective of this study was to determine whether metformin use is associated with a decreased risk of lung cancer ...

journal_title：Diabetes care

authors： Smiechowski BB,Azoulay L,Yin H,Pollak MN,Suissa S

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:This study compared heart rate variability (HRV) parameters in youth with and without type 1 diabetes and explored potential contributors of altered HRV. RESEARCH DESIGN AND METHODS:HRV parameters were measured among 354 youth with type 1 diabetes (mean age 18.8 years, diabetes duration 9.8 years, and mean A...

journal_title：Diabetes care

authors： Jaiswal M,Urbina EM,Wadwa RP,Talton JW,D'Agostino RB Jr,Hamman RF,Fingerlin TE,Daniels S,Marcovina SM,Dolan LM,Dabelea D

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic properties of a nonmydriatic 200° ultra-widefield scanning laser ophthalmoscope (SLO) versus mydriatic Early Treatment of Diabetic Retinopathy Study (ETDRS) 7-field photography for diabetic retinopathy (DR) screening. RESEARCH DESIGN AND METHODS:A consecutive series of 212 eyes of 1...

journal_title：Diabetes care

authors： Kernt M,Hadi I,Pinter F,Seidensticker F,Hirneiss C,Haritoglou C,Kampik A,Ulbig MW,Neubauer AS

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:The role of adiponectin in the natural history of diabetes is not well characterized. We set out to characterize prediagnosis trajectories of adiponectin in individuals who develop type 2 diabetes. RESEARCH DESIGN AND METHODS:In a case-cohort study (335 incident diabetes case and 2,474 noncase subjects) nest...

journal_title：Diabetes care

authors： Tabák AG,Carstensen M,Witte DR,Brunner EJ,Shipley MJ,Jokela M,Roden M,Kivimäki M,Herder C

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the effect of pharmacist care on cardiovascular disease (CVD) risk factors among outpatients with diabetes. RESEARCH DESIGN AND METHODS:MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials were...

journal_title：Diabetes care

authors： Santschi V,Chiolero A,Paradis G,Colosimo AL,Burnand B

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between self-reported diabetes and the risk of breast cancer (BC) and its interaction with moderate-intensity physical activity in pre- and postmenopausal Mexican women. RESEARCH DESIGN AND METHODS:A population-based case-control study was conducted using 1,000 incident case subje...

journal_title：Diabetes care

authors： Torres-Mejía G,Angeles-Llerenas A,Ortega-Olvera C,Lazcano-Ponce E,Ziv E,Pulido-Rodríguez J,García-Solis Mde J,Murillo-Zamora E,Vázquez-Lara J,Romieu I

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes i...

journal_title：Diabetes care

authors： Schou J,Tybjærg-Hansen A,Møller HJ,Nordestgaard BG,Frikke-Schmidt R

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To detect clinical correlates of cognitive abilities and white matter (WM) microstructural changes using diffusion tensor imaging (DTI) in young children with type 1 diabetes. RESEARCH DESIGN AND METHODS:Children, ages 3 to <10 years, with type 1 diabetes (n = 22) and age- and sex-matched healthy control sub...

journal_title：Diabetes care

authors： Aye T,Barnea-Goraly N,Ambler C,Hoang S,Schleifer K,Park Y,Drobny J,Wilson DM,Reiss AL,Buckingham BA

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:A key milestone in progress towards providing an efficacious and safe closed-loop artificial pancreas system for outpatient use is the development of fully automated, portable devices with fault detection capabilities to ensure patient safety. The ability to remotely monitor the operation of the closed-loop s...

journal_title：Diabetes care

authors： O'Grady MJ,Retterath AJ,Keenan DB,Kurtz N,Cantwell M,Spital G,Kremliovsky MN,Roy A,Davis EA,Jones TW,Ly TT

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To examine determinants of racial/ethnic differences in diabetes incidence among postmenopausal women participating in the Women's Health Initiative. RESEARCH DESIGN AND METHODS:Data on race/ethnicity, baseline diabetes prevalence, and incident diabetes were obtained from 158,833 women recruited from 1993-19...

journal_title：Diabetes care

authors： Ma Y,Hébert JR,Manson JE,Balasubramanian R,Liu S,Lamonte MJ,Bird CE,Ockene JK,Qiao Y,Olendzki B,Schneider KL,Rosal MC,Sepavich DM,Wactawski-Wende J,Stefanick ML,Phillips LS,Ockene IS,Kaplan RC,Sarto GE,Garcia L,Ho

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Adverse microbial exposures might contribute to diabetogenesis. We hypothesized that clinical periodontal disease (a manifestation of microbial exposures in dysbiotic biofilms) would be related to insulin resistance among diabetes-free participants. The roles of inflammatory mediation and effect modification ...

journal_title：Diabetes care

authors： Demmer RT,Squillaro A,Papapanou PN,Rosenbaum M,Friedewald WT,Jacobs DR Jr,Desvarieux M

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To compare the diagnostic accuracy and time expenditure of screening models based on glycated hemoglobin (HbA(1c)) level and psychometric measures for mood disorder (MD) among children with type 1 diabetes. RESEARCH DESIGN AND METHODS:With semistructured clinical interviews (Schedule for Affective Disorders ...

journal_title：Diabetes care

authors： Butwicka A,Fendler W,Zalepa A,Szadkowska A,Mianowska B,Gmitrowicz A,Młynarski W

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of switching from sitagliptin to liraglutide in metformin-treated adults with type 2 diabetes. RESEARCH DESIGN AND METHODS:In an open-label trial, participants randomized to receive either liraglutide (1.2 or 1.8 mg/day) or sitagliptin (100 mg/day), each added to metformin, ...

journal_title：Diabetes care

authors： Pratley RE,Nauck MA,Bailey T,Montanya E,Filetti S,Garber AJ,Thomsen AB,Furber S,Davies M,1860-LIRA-DPP-4 Study Group.

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Epidemiological studies and randomized clinical trials have demonstrated in various populations that resting heart rate (RHR) was an independent predictor of cardiovascular (CV) risk and all-cause mortality. However, few data specifically evaluated the relationship between RHR and long-term CV and renal compl...

journal_title：Diabetes care

authors： Miot A,Ragot S,Hammi W,Saulnier PJ,Sosner P,Piguel X,Torremocha F,Marechaud R,Hadjadj S

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To determine whether adolescents with type 1 diabetes have left ventricular functional changes at rest and during acute exercise and whether these changes are affected by metabolic control and diabetes duration. RESEARCH DESIGN AND METHODS:The study evaluated 53 adolescents with type 1 diabetes and 22 contro...

journal_title：Diabetes care

authors： Gusso S,Pinto TE,Baldi JC,Robinson E,Cutfield WS,Hofman PL

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Diabetes is a major predictor of death from heart disease and stroke; its impact on nonvascular mortality, including specific cancers, is less understood. We examined the association of diabetes with cause-specific mortality, including deaths from specific cancers. RESEARCH DESIGN AND METHODS:A prospective c...

journal_title：Diabetes care

authors： Campbell PT,Newton CC,Patel AV,Jacobs EJ,Gapstur SM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To determine the usefulness of measuring hemoglobin A(1c) (A1C), alone or combined with the fasting glucose test, compared with the oral glucose tolerance test (OGTT) for the reassessment of the carbohydrate metabolism status in postpartum women with a history of gestational diabetes mellitus (GDM). RESEARCH...

journal_title：Diabetes care

authors： Picón MJ,Murri M,Muñoz A,Fernández-García JC,Gomez-Huelgas R,Tinahones FJ

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Compare differences in health-related quality of life among blacks and whites to examine if race, diabetes, and visual impairment (VI) present a triple disadvantage in terms of quality-adjusted life expectancy. RESEARCH DESIGN AND METHODS:Data were analyzed from the 2000-2003 Medical Expenditure Panel Survey...

journal_title：Diabetes care

authors： McCollister KE,Zheng DD,Fernandez CA,Lee DJ,Lam BL,Arheart KL,Galor A,Ocasio M,Muennig P

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to pioglitazone in type 2 diabetes inadequately controlled on pioglitazone. RESEARCH DESIGN AND METHODS:Treatment-naive patients or those receiving metformin, sulfonylurea, or thiazolidinedione entered a...

journal_title：Diabetes care

authors： Rosenstock J,Vico M,Wei L,Salsali A,List JF

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Roux-en-Y gastric bypass (RYGB) ameliorates type 2 diabetes in severely obese patients through mechanisms beyond just weight loss, and it may benefit less obese diabetic patients. We determined the long-term impact of RYGB on patients with diabetes and only class I obesity. RESEARCH DESIGN AND METHODS:Sixty-...

journal_title：Diabetes care

authors： Cohen RV,Pinheiro JC,Schiavon CA,Salles JE,Wajchenberg BL,Cummings DE

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group. RESEARCH DESIGN AND METHODS:In a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at Kaiser Permanente of Northern California,...

journal_title：Diabetes care

authors： Hedderson M,Ehrlich S,Sridhar S,Darbinian J,Moore S,Ferrara A

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:To determine whether immunocomplexes (ICs) containing advanced glycation end product (AGE)-LDL (AGE-LDL) and oxidized LDL (oxLDL) contribute to the development of retinopathy over a 16-year period in subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS:Levels of AGE-LDL and oxLDL in ICs were measured i...

journal_title：Diabetes care

authors： Lopes-Virella MF,Baker NL,Hunt KJ,Lyons TJ,Jenkins AJ,Virella G,DCCT\/EDIC Study Group.

更新日期：2012-06-01 00:00:00